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中文名称： KEAP1 抗原（重组蛋白）
英文名称： KEAP1 Antigen (Recombinant Protein)
别 名： kelch-like ECH-associated protein 1; INrf2; KLHL19
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
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Fusion protein corresponding to C terminal 300 amino acids of human KEAP1 |
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Full name: |
kelch-like ECH-associated protein 1 |
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Synonyms: |
INrf2; KLHL19 |
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Swissprot: |
Q14145 |
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Gene Accession: |
BC002417 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. |
