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中文名称： ATP6V0D1 抗原（重组蛋白）
别 名： ATPase H+ transporting V0 subunit d1; P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD
相关类别： 抗原
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Full name: |
ATPase H+ transporting V0 subunit d1 |
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Synonyms: |
P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD |
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Swissprot: |
P61421 |
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Gene Accession: |
BC008861 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. |
