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ÖÐÎÄÃû³Æ£ºÍÿ¹ALPL¶à¿Ë¡¿¹Ìå

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Anti-ALPL rabbit polyclonal antibody

±ð      Ãû£º HOPS,TNSALP

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´¢      ´æ£º Àä¶³£¨-20¡æ£©

¿¹      Ô­£º ALPL

ËÞ      Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.

Applications:

ELISA, IHC

Name of antibody:

ALPL

Immunogen:

Fusion protein of human ALPL

Full name:

alkaline phosphatase, biomineralization associated

Synonyms:

HOPS; TNAP; TNALP; APTNAP; TNSALP; AP-TNAP

SwissProt:

P05186

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human liver cancer

IHC Recommend dilution:

200-400





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