购物车
帮助
021-54845833/15800441009
中文名称 ： 兔抗PCP4多克隆抗体
英文名称 ： Anti-PCP4 rabbit polyclonal antibody
别 名 ： PEP-19
相关类别 ： 一抗
抗 原 ： PCP4
储 存 ： 冷冻（-20℃）
宿 主 ： Rabbit
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
|
Background: |
PCP-4 (Purkinje cell protein 4), also known as PEP-19, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer’s disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
PCP4 |
|
Immunogen: |
Fusion protein of human PCP4 |
|
Full name: |
purkinje cell protein 4 |
|
Synonyms： |
PEP-19 |
|
SwissProt: |
P48539 |
|
ELISA Recommended dilution: |
2000-10000 |
|
IHC positive control: |
Human cervical cancer and human tonsil |
|
IHC Recommend dilution: |
100-300 |
|
WB Predicted band size: |
7 kDa |
|
WB Positive control: |
Mouse brain tissue |
|
WB Recommended dilution: |
500-2000 |
