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Background: |
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
TP53I11 |
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Immunogen: |
Synthetic peptide of human TP53I11 |
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Full name: |
tumor protein p53 inducible protein 11 |
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Synonyms： |
PIG11 |
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SwissProt: |
O14683 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
21 kDa |
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WB Positive control: |
Jurkat cells |
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WB Recommended dilution: |
500-2000 |
