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Background: |
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TLE5 |
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Immunogen: |
Fusion protein of human TLE5 |
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Full name: |
TLE family member 5, transcriptional modulator |
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Synonyms: |
AES; GRG; ESP1; GRG5; AES-1; AES-2; Grg-5 |
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SwissProt: |
Q08117 |
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IHC positive control: |
Human liver cancer and Human gastric cancer |
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IHC Recommend dilution: |
25-100 |
