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Background: |
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ICAM3 |
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Immunogen: |
Synthetic peptide of human ICAM3 |
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Full name: |
intercellular adhesion molecule 3 |
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Synonyms: |
CD50; CDW50; ICAM-R |
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SwissProt: |
P32942 |
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IHC positive control: |
Human gastric cancer and human brain |
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IHC Recommend dilution: |
25-100 |
