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ÖÐÎÄÃû³Æ£º Íÿ¹ANAPC15¶à¿Ë¡¿¹Ìå 

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Anti-ANAPC15 rabbit polyclonal antibody

±ð      Ãû£º APC15; HSPC020; C11orf51

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ËÞ      Ö÷£º Rabbit

¿¹      Ô­£º ANAPC15

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.

Applications:

ELISA, IHC

Name of antibody:

ANAPC15

Immunogen:

Synthetic peptide of human ANAPC15

Full name:

anaphase promoting complex subunit 15

Synonyms:

APC15; HSPC020; C11orf51

SwissProt:

P60006

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and human gastric cancer

IHC Recommend dilution:

40-200





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