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Ó¢ÎÄÃû³Æ£º Anti-ANAPC15 rabbit polyclonal antibody
±ð Ãû£º APC15; HSPC020; C11orf51
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º ANAPC15
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ANAPC15 |
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Immunogen: |
Synthetic peptide of human ANAPC15 |
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Full name: |
anaphase promoting complex subunit 15 |
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Synonyms: |
APC15; HSPC020; C11orf51 |
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SwissProt: |
P60006 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human ovarian cancer and human gastric cancer |
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IHC Recommend dilution: |
40-200 |
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021-54845833/15800441009
