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英文名称： Anti-HDAC5 (Phospho-Ser498) rabbit polyclonal antibody
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
抗 原： HDAC5 (Phospho-Ser498)
标 记 物： Unconjugate
技术规格
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Background: |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
WB, IHC |
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Name of antibody: |
HDAC5 (Phospho-Ser498) |
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Immunogen: |
Synthetic peptide of human HDAC5 (Phospho-Ser498) |
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Full name: |
histone deacetylase 5 (Phospho-Ser498) |
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Synonyms： |
HD5; NY-CO-9 |
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SwissProt: |
Q9UQL6 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
122 kDa |
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WB Positive control: |
293 cells untreated or treated with serum starvation |
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WB Recommended dilution: |
500-1000 |
