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别 名： ILT3; LIR5; CD85K; ILT-3; LIR-5
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Background: |
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. |
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Applications: |
IF |
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Name of antibody: |
LILRB4 |
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Immunogen: |
Synthesized peptide derived from internal of human LILRB4. |
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Full name: |
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
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Synonyms： |
ILT3; LIR5; CD85K; ILT-3; LIR-5 |
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SwissProt: |
Q8NHJ6 |
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IF positive control: |
A549 cells |
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IF Recommend dilution: |
100-500 |
