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Background: |
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. |
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Applications: |
WB, IHC |
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Name of antibody: |
CTNNB1(phospho-Tyr333) |
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Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 333 (Y-T-Y(p)-E-K) derived from Human β-catenin |
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Full name: |
catenin (cadherin-associated protein), beta 1, 88kDa |
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Synonyms： |
CTNNB; MRD19; armadillo |
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SwissProt: |
P35222 |
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IHC positive control: |
Human lung carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
85 kDa |
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WB Positive control: |
293 cells lysates untreated or treated with FSK |
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WB Recommended dilution: |
500-1000 |
