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    ÖÐÎÄÃû³Æ£º  CYBA¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º CYBA Antigen (Recombinant Protein)

    ±ð      Ãû£º p22-PHOX

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    Fusion protein corresponding to a region derived from C terminal 250 amino acids of human CYBA


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    Full name:

    cytochrome b-245, alpha polypeptide

    Synonyms:

    p22-PHOX

    Swissprot:

    P13498

    Gene Accession:

    NP_000092

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.

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