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ÖÐÎÄÃû³Æ£º PAX8¿¹Ô­£¨ÖØ×éµ°°×£©

Ó¢ÎÄÃû³Æ£º PAX8 Antigen (Recombinant Protein)

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Fusion protein corresponding to C terminal 250 amino acids of human PAX8

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Full name:

Paired box 8

Swissprot:

Q06710

Gene Accession:

BC001060

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

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