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中文名称：PHF5A抗原（重组蛋白）
英文名称： PHF5A Antigen (Recombinant Protein)
别 名： INI; Rds3; SF3B7; SAP14b; SF3b14b; bK223H9.2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 1-110 amino acids of human PHF5A |
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Full name: |
PHD finger protein 5A |
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Synonyms: |
INI; Rds3; SF3B7; SAP14b; SF3b14b; bK223H9.2 |
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Swissprot: |
Q7RTV0 |
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Gene Accession: |
BC007321 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. |
