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    Ó¢ÎÄÃû³Æ£º KRT2 Antigen (Recombinant Protein)

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    Fusion protein corresponding to a region derived from 233-487 amino acids of human KRT2


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    Full name:

    keratin 2

    Synonyms:

    K2e, KRTE, CK-2e, KRT2A, KRT2E

    Swissprot:

    P35908

    Gene Accession:

    BC096294

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.


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