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CNGA2 Antigen (Recombinant Protein)

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Fusion protein corresponding to a region derived from 475-662 amino acids of human CNGA2


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Full name:

cyclic nucleotide gated channel alpha 2

Synonyms:

CNCA, CNG2, CNCA1, OCNC1, OCNCa, OCNCALPHA

Swissprot:

Q16280

Gene Accession:

BC126302

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.


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