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Ó¢ÎÄÃû³Æ£º UGT2B4 Antigen (Recombinant Protein)

±ð     Ãû£º UDP glucuronosyltransferase 2 family, polypeptide B4; HLUG25; UDPGTH1; UGT2B11; UDPGT2B4; UDPGTh-1

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Fusion protein corresponding to C terminal 200 amino acids of human UGT2B4

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Full name:

UDP glucuronosyltransferase 2 family, polypeptide B4

Synonyms:

HLUG25; UDPGTH1; UGT2B11; UDPGT2B4; UDPGTh-1

Swissprot:

P06133

Gene Accession:

BC026264

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.


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