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中文名称：MRPL48 抗原（重组蛋白）
英文名称： MRPL48 Antigen (Recombinant Protein)
别 名： mitochondrial ribosomal protein L48; L48MT; CGI-118; HSPC290; MRP-L48
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 29-212 amino acids of human MRPL48 |
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Full name: |
mitochondrial ribosomal protein L48 |
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Synonyms: |
L48MT; CGI-118; HSPC290; MRP-L48 |
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Swissprot: |
Q96GC5 |
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Gene Accession: |
BC009764 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. |
