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ÖÐÎÄÃû³Æ£º KLF7¿¹Ô­£¨ÖØ×éµ°°×£©

Ó¢ÎÄÃû³Æ£º KLF7 Antigen (Recombinant Protein)

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Full length fusion protein

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Full name:

Kruppel-like factor 7 (ubiquitous)

Synonyms:

UKLF

Swissprot:

O75840

Gene Accession:

BC012919

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.




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