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中文名称： UBE2A 抗原（重组蛋白）
英文名称： UBE2A Antigen (Recombinant Protein)
别 名： ubiquitin conjugating enzyme E2 A; UBC2; HHR6A; MRXSN; RAD6A; MRXS30
储 存： 冷冻（-20℃）
相关类别：抗原
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Full name: |
ubiquitin conjugating enzyme E2 A |
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Synonyms: |
UBC2; HHR6A; MRXSN; RAD6A; MRXS30 |
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Swissprot: |
P49459 |
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Gene Accession: |
BC010175 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. |
