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CALCR Antigen (Recombinant Protein)

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Fusion protein corresponding to a region derived from 26-153 amino acids of human CALCR


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Full name:

calcitonin receptor

Synonyms:

CRT, CTR, CT-R, CTR1

Swissprot:

P30988

Gene Accession:

BC069611

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.


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