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中文名称： HSD17B12抗原（重组蛋白）
英文名称： HSD17B12 Antigen (Recombinant Protein)
别 名： KAR; SDR12C1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 25-180 amino acids of human HSD17B12 |
技术规格：
|
Full name: |
hydroxysteroid (17-beta) dehydrogenase 12 |
|
Synonyms: |
KAR; SDR12C1 |
|
Swissprot: |
Q53GQ0 |
|
Gene Accession: |
BC012043 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. |
