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Ó¢ÎÄÃû³Æ£º SUFU Antigen (Recombinant Protein)

±ð      Ãû£º SUFU negative regulator of hedgehog signaling; SUFUH; JBTS32; SUFUXL; PRO1280

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Fusion protein corresponding to C terminal 250 amino acids of human SUFU

 
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Full name:

SUFU negative regulator of hedgehog signaling

Synonyms:

SUFUH; JBTS32; SUFUXL; PRO1280

Swissprot:

Q9UMX1

Gene Accession:

BC013291

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.


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