购物车
帮助
021-54845833/15800441009
中文名称：DCT 抗原（重组蛋白）
英文名称： DCT Antigen (Recombinant Protein)
别 名： dopachrome tautomerase; TRP-2; TYRP2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 222-472 amino acids of human DCT |
|
Full name: |
dopachrome tautomerase |
|
Synonyms: |
TRP-2; TYRP2 |
|
Swissprot: |
P40126 |
|
Gene Accession: |
BC028311 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The human TYRP2 protein has 83% identity and 90% similarity to the mouse sequence and has all the structural characteristics of the tyrosinase protein family, including a signal peptide, 15 conserved cysteine residues, 2 copper-binding domains, and a C-terminal membrane-spanning region. Northern blot analysis showed that TYRP2 is expressed at high levels in human melanoma cells. Its expression is regulated by the microphthalmia-associated transcription factor (MITF). |
