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中文名称： ZCCHC9 抗原（重组蛋白）
英文名称： ZCCHC9 Antigen (Recombinant Protein)
别 名： zinc finger, CCHC domain containing 9; PPP1R41
储 存： 冷冻（-20℃）
相关类别：抗原
概 述
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Full name: |
zinc finger, CCHC domain containing 9 |
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Synonyms: |
PPP1R41 |
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Swissprot: |
Q8N567 |
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Gene Accession: |
BC032736 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC9 (zinc finger, CCHC domain containing 9) is a 271 amino acid protein that contains four CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC9 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
