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中文名称： FTO抗原（重组蛋白）
英文名称： FTO Antigen (Recombinant Protein)
别 名： ALKBH9
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 456-505 amino acids of human FTO |
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Full name: |
fat mass and obesity associated |
|
Synonyms: |
ALKBH9 |
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Swissprot: |
Q9C0B1 |
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Gene Accession: |
BC003583 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |
