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中文名称： C1GALT1C1抗原（重组蛋白）
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Full name: |
C1GALT1 specific chaperone 1 |
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Synonyms: |
TNPS; COSMC; MST143; C1GALT2; HSPC067; C38H2-L1 |
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Swissprot: |
Q96EU7 |
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Gene Accession: |
BC011930 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. |
