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      ÖÐÎÄÃû³Æ£º  GLIPR1¿¹Ô­£¨ÖØ×éµ°°×£©

      Ó¢ÎÄÃû³Æ£º GLIPR1 Antigen (Recombinant Protein)

      ±ð  Ãû£º GLIPR; RTVP1; CRISP7

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      Fusion protein corresponding to a region derived from 22-230 amino acids of human GLIPR1


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      Full name:

      GLI pathogenesis-related 1

      Synonyms:

      GLIPR; RTVP1; CRISP7

      Swissprot:

      P48060

      Gene Accession:

      BC012510

      Purity:

      >85%, as determined by Coomassie blue stained SDS-PAGE

      Expression system:

      Escherichia coli

      Tags:

      His tag C-Terminus, GST tag N-Terminus

      Background:

      This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.


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