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中文名称：ANAPC2 抗原（重组蛋白）
英文名称： ANAPC2 Antigen (Recombinant Protein)
别 名： anaphase promoting complex subunit 2; APC2; RP11-350O14.5
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 300 amino acids of human ANAPC2 |
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Full name: |
anaphase promoting complex subunit 2 |
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Synonyms: |
APC2; RP11-350O14.5 |
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Swissprot: |
Q9UJX6 |
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Gene Accession: |
BC032503 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. |
