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Ó¢ÎÄÃû³Æ£º ADAMTSL2 Antigen (Recombinant Protein)

±ð      Ãû£º ADAMTS-like 2; GPHYSD1

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Fusion protein corresponding to C terminal 250 amino acids of human ADAMTSL2

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Full name:

ADAMTS-like 2

Synonyms:

GPHYSD1

Swissprot:

Q86TH1

Gene Accession:

BC050544

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.


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