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Ó¢ÎÄÃû³Æ£º ADAMTSL2 Antigen (Recombinant Protein)
±ð Ãû£º ADAMTS-like 2; GPHYSD1
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Fusion protein corresponding to C terminal 250 amino acids of human ADAMTSL2 |
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Full name: |
ADAMTS-like 2 |
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Synonyms: |
GPHYSD1 |
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Swissprot: |
Q86TH1 |
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Gene Accession: |
BC050544 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. |
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021-54845833/15800441009
