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AMPH Antigen (Recombinant Protein)

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Fusion protein corresponding to C terminal 250 amino acids of human AMPH


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Full name:

amphiphysin

Synonyms:

AMPH1

Swissprot:

P49418

Gene Accession:

BC034376

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.




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