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中文名称：BEX2抗原（重组蛋白）
英文名称： BEX2 Antigen (Recombinant Protein)
别 名： BEX1; DJ79P11.1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 1-128 amino acids of human BEX2 |
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Full name: |
brain expressed X-linked 2 |
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Synonyms: |
BEX1; DJ79P11.1 |
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Swissprot: |
Q9BXY8 |
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Gene Accession: |
BC015522 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. |
