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中文名称：IGF2抗原（重组蛋白）
英文名称： IGF2 Antigen (Recombinant Protein)
别 名： GRDF; IGF-II; PP9974; C11orf43
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to a region derived from 25-180 amino acids of human IGF2 |
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Full name: |
insulin like growth factor 2 |
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Synonyms: |
GRDF; IGF-II; PP9974; C11orf43 |
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Swissprot: |
P01344 |
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Gene Accession: |
BC000531 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
