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    Ó¢ÎÄÃû³Æ£º DIRAS3 Antigen (Recombinant Protein)

    ±ð  Ãû£º ARHI; NOEY2

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    Fusion protein corresponding to a region derived from 1-226 amino acids of human DIRAS3


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    Full name:

    DIRAS family, GTP-binding RAS-like 3

    Synonyms:

    ARHI; NOEY2

    Swissprot:

    O95661

    Gene Accession:

    BC005362

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.


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