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中文名称： IL2RB抗原（重组蛋白）
英文名称： IL2RB Antigen (Recombinant Protein)
别 名： CD122; IL15RB; P70-75
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 41-240 amino acids of human IL2RB |
|
Full name: |
interleukin 2 receptor, beta |
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Synonyms: |
CD122; IL15RB; P70-75 |
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Swissprot: |
P14784 |
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Gene Accession: |
BC025691 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. |
