购物车
帮助
021-54845833/15800441009
中文名称 : 兔抗ZFAND5多克隆抗体
技术规格
Background:
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Applications:
ELISA, WB, IHC
Name of antibody:
ZFAND5
Immunogen:
Full length fusion protein
Full name:
zinc finger, AN1-type domain 5
Synonyms：
ZA20D2; ZNF216; ZFAND5A
SwissProt:
O76080
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human thyroid cancer and human lung cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
23 kDa
WB Positive control:
Mouse fat tissue lysate
WB Recommended dilution:
500-2000
