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中文名称： 兔抗POLH多克隆抗体
英文名称： Anti-POLH rabbit polyclonal antibody
别 名： DNA polymerase eta; XPV; XP-V; RAD30; RAD30A
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： POLH
反应种属： Human, Mouse
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
POLH |
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Immunogen: |
Fusion protein of human POLH |
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Full name: |
DNA polymerase eta |
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Synonyms: |
XPV; XP-V; RAD30; RAD30A |
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SwissProt: |
Q9Y253 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human thyroid cancer |
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IHC Recommend dilution: |
50-300 |
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WB Predicted band size: |
78 kDa |
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WB Positive control: |
A172, 231, Jurkat, HepG2 and Hela cell lysates |
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WB Recommended dilution: |
500-2000 |
