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中文名称： 兔抗POLG多克隆抗体
英文名称： Anti-POLG rabbit polyclonal antibody
别 名： EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2
相关类别： 一抗
抗 原： POLG
储 存： 冷冻（-20℃）
宿 主： Rabbit
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
POLG |
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Immunogen: |
Synthetic peptide corresponding to a region derived from 1197-1211 amino acids of human POLG |
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Full name: |
DNA polymerase gamma, catalytic subunit |
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Synonyms: |
PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B |
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SwissProt: |
P54098 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC Positive control: |
Human liver cancer;Human gastric cancer |
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IHC Recommended dilution: |
10-50 |
