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ÖÐÎÄÃû³Æ£ºÍÿ¹ZUP1¶à¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-ZUP1 rabbit polyclonal antibody

±ð       Ãû£º zinc finger containing ubiquitin peptidase 1; DUB;

¿¹       Ô­£º ZUP1

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´¢     ´æ£º Àä¶³£¨-20¡æ£©

ËÞ      Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human, Mouse, Rat

±ê  ¼Ç  Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018]

Applications:

ELISA, IHC

Name of antibody:

ZUP1

Immunogen:

Fusion protein of human ZUP1

Full name:

zinc finger containing ubiquitin peptidase 1

Synonyms:

DUB; ZUFSP; C6orf113

SwissProt:

Q96AP4

IHC positive control:

Human esophagus cancer and Human lung cancer

IHC Recommend dilution:

25-100






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