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    • Íÿ¹CTNND2¶à¿Ë¡¿¹Ìå

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    Íÿ¹CTNND2¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º Anti-CTNND2 rabbit polyclonal antibody

    ±ð      Ãû£º catenin delta 2; GT24; NPRAP

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    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º Rabbit

    ¿¹      Ô­£º CTNND2

    ·´Ó¦ÖÖÊô£º Human, Mouse

    ±ê  ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Applications:

    ELISA, WB

    Name of antibody:

    CTNND2

    Immunogen:

    Synthetic peptide of human CTNND2

    Full name:

    catenin delta 2

    Synonyms:

    GT24; NPRAP

    SwissProt:

    Q9UQB3

    ELISA Recommended dilution:

    5000-10000

    WB Predicted band size:

    133 kDa

    WB Positive control:

    Mouse brain tissue and Human cerebrum tissue lysates

    WB Recommended dilution:

    200-1000




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