Name: RHOH抗原（重组蛋白）
Brand: 通蔚生物

中文名称： RHOH抗原（重组蛋白）

英文名称： RHOH Antigen (Recombinant Protein)

别名： TTF; ARHH

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to a region derived from 1-191 amino acids of human RHOH

技术规格

Full name:	ras homolog family member H
Synonyms:	TTF; ARHH
Swissprot:	Q15669
Gene Accession:	BC014261
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.

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