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Ó¢ÎÄÃû³Æ£º RIOX2 Antigen (Recombinant Protein)

±ð     Ãû£º ribosomal oxygenase 2; ROX; MDIG; MINA; NO52; JMJD10; MINA53

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Fusion protein corresponding to a region derived from 266-465 amino acids of human RIOX2

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Full name:

ribosomal oxygenase 2

Synonyms:

ROX; MDIG; MINA; NO52; JMJD10; MINA53

Swissprot:

Q8IUF8

Gene Accession:

BC014928

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.


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