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±ð Ãû£º ribosomal oxygenase 2; ROX; MDIG; MINA; NO52; JMJD10; MINA53
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Full name: |
ribosomal oxygenase 2 |
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Synonyms: |
ROX; MDIG; MINA; NO52; JMJD10; MINA53 |
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Swissprot: |
Q8IUF8 |
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Gene Accession: |
BC014928 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
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