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    ÖÐÎÄÃû³Æ£ºÍÿ¹BLVRB¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-BLVRB rabbit polyclonal antibody

    ±ð      Ãû£º FLR; BVRB; SDR43U1; HEL-S-10

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º Rabbit

    ¿¹      Ô­£º BLVRB

    ·´Ó¦ÖÖÊô£º Human, Mouse

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    BLVRB (biliverdin reductase B or BVR-B), also known as flavin reductase (FR), NADPH-dependent diaphorase, Biliverdin-IX ¡Ò-reductase or green heme-binding protien (GHBP) is an enzyme involved in fetal heme metabolism. It is dependent on NADPH and is responsible for catalyzing the transfer of electrons to flavins from reduced pyridine nucleotides. BLVRB exists as a monomer, localizes to the cytoplasm and is highly expressed in fetal liver and adult erythrocytes and, to a lesser extent, in heart, lung, cerebrum and adrenal gland. In liver, BLVRB functions to convert biliverdin (isoforms IX¡Ò, IX and IX ) to bilirubin. BLVRB contains one binding site for all of its substrates and predominantly interacts with them through hydrophobic interactions. BLVRB also exhibits ferric reductase activity. In addition, it is commonly used as a reliable marker for NOS.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    BLVRB

    Immunogen:

    Synthetic peptide of human BLVRB

    Full name:

    biliverdin reductase B

    Synonyms:

    FLR; BVRB; SDR43U1; HEL-S-10

    SwissProt:

    P30043

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human tonsil and human colorectal cancer

    IHC Recommend dilution:

    40-200

    WB Predicted band size:

    22 kDa

    WB Positive control:

    A549 and K562 cell lysate

    WB Recommended dilution:

    500-2000




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