购物车
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021-54845833/15800441009
中文名称：兔抗DAB2多克隆抗体
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Background: |
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
DAB2 |
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Immunogen: |
Fusion protein of human DAB2 |
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Full name: |
DAB adaptor protein 2 |
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Synonyms: |
DOC2; DOC-2 |
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SwissProt: |
P98082 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human tonsil and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
82 kDa |
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WB Positive control: |
Hela cells |
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WB Recommended dilution: |
500-2000 |
