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Background: |
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
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Applications: |
WB, IHC |
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Name of antibody: |
CTBP1(Phospho-Ser422) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 422(A-P-S(p)-P-G) derived from Human CtBP1. |
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Full name: |
C-terminal binding protein 1 |
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Synonyms： |
BARS |
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SwissProt: |
Q13363 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
48 kDa |
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WB Positive control: |
Jurkat cells lysates treated with TNF |
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WB Recommended dilution: |
500-1000 |
