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    • Íÿ¹PDE1B¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º Íÿ¹PDE1B¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º Anti-PDE1B rabbit polyclonal antibody


    ±ð       Ãû£º PDE1B1; PDES1B


    Ïà¹ØÀà±ð£º Ò»¿¹


    ´¢       ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â


    ËÞ      Ö÷£º Rabbit


    ¿¹      Ô­£º PDE1B


    ·´Ó¦ÖÖÊô£º Human, Mouse, Rat


    ±ê  ¼Ç  Î Unconjugate


    ¿Ë¡ÀàÐÍ£º rabbit polyclonal


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    Background:

    The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Applications:

    WB

    Name of antibody:

    PDE1B

    Immunogen:

    Fusion protein of human PDE1B

    Full name:

    phosphodiesterase 1B, calmodulin-dependent

    Synonyms£º

    PDE1B1; PDES1B

    SwissProt:

    Q01064

    WB Predicted band size:

    61 kDa

    WB Positive control:

    NCL and THP1 cells, mouse brain and spleen tissue, spinal cord tissue

    WB Recommended dilution:

    500-2000




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