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Background: |
THAP6 (THAP domain-containing protein 6) is a 222 amino acid protein that contains one THAP-type zinc finger and exists as two alternatively spliced isoforms. The gene that encodes THAP6 consists of approximately 36,528 bases and maps to human chromosome 4q21.1. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is encoded by a gene that maps to chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
THAP6 |
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Immunogen: |
Full length fusion protein |
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Full name: |
THAP domain containing 6 |
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SwissProt: |
Q8TBB0 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human esophagus cancer |
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IHC Recommend dilution: |
25-100 |
