ÖÐÎÄÃû³Æ£º Íÿ¹PITX2¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-PITX2 rabbit polyclonal antibody
±ð Ãû£º RS; RGS; ARP1; Brx1; IDG2; IGDS; IHG2; PTX2; RIEG; IGDS2; IRID2; Otlx2; RIEG1
Ïà¹ØÀà±ð£º Ò»¿¹
¿¹ Ô£º PITX2
´¢ ´æ£º Àä¶³£¨-20¡æ£©
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
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Applications: |
ELISA, WB |
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Name of antibody: |
PITX2 |
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Immunogen: |
Fusion protein of human PITX2 |
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Full name: |
paired-like homeodomain 2 |
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Synonyms£º |
RS; RGS; ARP1; Brx1; IDG2; IGDS; IHG2; PTX2; RIEG; IGDS2; IRID2; Otlx2; RIEG1 |
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SwissProt: |
Q99697 |
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ELISA Recommended dilution: |
2000-5000 |
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WB Predicted band size: |
35 kDa |
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WB Positive control: |
HepG2 cells |
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WB Recommended dilution: |
500-2000 |

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