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ÖÐÎÄÃû³Æ£º Íÿ¹NCOR1¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-NCOR1 rabbit polyclonal antibody


±ð       Ãû£º N-CoR, TRAC1, N-CoR1, hN-CoR


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´¢      ´æ£º Àä¶³£¨-20¡æ£©


ËÞ      Ö÷£º Rabbit


¿¹      Ô­£º NCOR1


·´Ó¦ÖÖÊô£º Human


±ê  ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal


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Background:

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Applications:

ELISA, IHC

Name of antibody:

NCOR1

Immunogen:

Synthetic peptide of human NCOR1

Full name:

nuclear receptor corepressor 1

Synonyms£º

N-CoR, TRAC1, N-CoR1, hN-CoR

SwissProt:

O75376

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human cervical cancer and Human tonsil

IHC Recommend dilution:

100-300




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