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021-54845833/15800441009
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Background: |
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
VPS37A |
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Immunogen: |
Fusion protein of human VPS37A |
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Full name: |
VPS37A subunit of ESCRT-I |
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Synonyms: |
HCRP1; PQBP2; SPG53 |
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SwissProt: |
Q8NEZ2 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer and Human prostate cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
44 kDa |
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WB Positive control: |
Human bladder carcinoma and fetal liver tissue |
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WB Recommended dilution: |
500-2000 |
